Found 13 matching trials
Oral SAR245408 (XL147) and Oral MSC1936369B in Patients With Locally Advanced or Metastatic Solid Tumors PHASE1 Primary Objective:
\- To determine the maximum tolerated dose(s) (MTD) and...
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Investigational Site Number 840001
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Study of XL147 (SAR245408) in Combination With Trastuzumab or Paclitaxel and Trastuzumab in Subjects With Metastatic Breast Cancer Who Have Progressed on a Previous Trastuzumab-based Regimen PHASE1 Phase 1 of this study will evaluate the maximum tolerated dose (MTD) of XL1...
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Investigational Site Number 1537
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Open Label Treatment Extension Study With SAR245408 or SAR245409 as a Monotherapy or as a Combination Regimen PHASE1 Primary Objective:
The purpose of this study was to determine the long ter...
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Investigational Site Number 840010
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Safety and Pharmacokinetics of SAR245408 Daily Oral in Patients With Solid Tumors PHASE1 Primary Objective:
\- To confirm safety and tolerability of global recomme...
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Investigational Site Number 392002
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Study of XL147 (SAR245408) or XL765 (SAR245409) in Combination With Letrozole in Subjects With Breast Cancer PHASE1 Phase 1 of this study will evaluate the maximum tolerated dose (MTD) of XL1...
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Investigational Site Number 1537
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Safety Study of XL147 (SAR245408), in Combination With Paclitaxel and Carboplatin in Adults With Solid Tumors PHASE1 The purpose of this study is to evaluate the safety and tolerability of XL1...
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Investigational Site Number
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A Study of Investigational SAR256212 in Combination With SAR245408 in Patients With Solid Tumor Cancers PHASE1 Primary Objective:
* To determine the maximum tolerated dose (MTD) and rec...
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Investigational Site Number 840001
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A Study of the Safety and Pharmacokinetics of SAR245408 Tablets in Patients With Solid Tumors or Lymphoma PHASE1 Primary Objective:
\- To assess the safety, tolerability and plasma pharma...
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Investigational Site Number 056001
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Safety Study of XL647 and XL147 Administered in Combination Daily in Adults With Solid Tumors PHASE1 The purpose of this study is to determine the safety, tolerability, and hig...
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Memorial Sloan Kettering Cancer Center
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Study of XL147 (SAR245408) in Advanced or Recurrent Endometrial Carcinoma PHASE2 There has not been any systemic therapy approved in the United States or in...
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Investigational Site Number 1526
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